A brain drain is the migration of highly skilled or educated individuals from one country to another, often in search of better job opportunities or working conditions. Brain drain can have a negative impact on the country of origin, as it can lead to a loss of skilled workers and a depletion of the country's human capital. It can also have a negative impact on the economy, as it can lead to a loss of knowledge and expertise and make it more difficult for the country to develop and innovate.